CBD is one of the most exciting new restorative and balancing compounds available today, but many consumers are concerned about taking a CBD oil product that contains THC.

CBD and THC are both cannabinoids, the active compounds that provide the effects from ingesting cannabis. Adding cannabinoids like CBD to your diet is widely acknowledged as beneficial for supporting homeostasis in the body. However, there are many varying opinions on the ideal way to go about supplementing your diet with cannabinoids.

Here we compare CBD and THC and help answer the question: Should I take a CBD supplement with or without THC?


As we mentioned above, both CBD and THC are cannabinoids – or more specifically, phytocannabinoids since they are plant based. Your body produces similar compounds, called endocannabinoids. Phytocannabinoids mimic the structure of your endocannabinoids, allowing us to supplement our body’s own cannabinoids with those from the cannabis plant.

There are at least 100 known cannabinoids. THC and CBD are the most prevalent phytocannabinoids found in nature. They are also the most well-known since their effects are the most understood by science.

One of the key differences between CBD and THC is that THC, found in greater quantities in marijuana, is psychoactive (causes a high) and CBD, found in greater quantities in the hemp plant, is non-psychoactive. You can learn more about the differences between hemp and marijuana on our blog.


In hemp-derived CBD oil products, THC is present in only trace levels, far below the psychoactive threshold. Because CBD produces no known negative side effects, it is regarded as safe for use by anyone in your family.

Both CBD and THC interact with the body’s endocannabinoid system through specialized cannabinoid receptors to provide their beneficial effects, mimicking our own naturally occurring cannabinoids. There are two main types of cannabinoid receptors, CB1 and CB2, found in the body’s central and peripheral nervous systems.

THC has the highest affinity for binding with CB1 receptors. CBD, on the other hand, doesn’t bind directly to either cannabinoid receptors. Instead, it acts indirectly against cannabinoid agonists. CBD also interacts with various other receptors throughout the body, like the 5-HT1A receptor, which is linked to serotonin.

It is through this interaction with various systems within the body that these cannabinoids promote balance in our lives. Although they interact with the body through different channels, both THC and CBD are tied to maintaining homeostasis.